SCD1 promotes lipid mobilization in subcutaneous white adipose tissue
نویسندگان
چکیده
منابع مشابه
Circadian Regulation of Lipid Mobilization in White Adipose Tissues
In mammals, a network of circadian clocks regulates 24-h rhythms of behavior and physiology. Circadian disruption promotes obesity and the development of obesity-associated disorders, but it remains unclear to which extent peripheral tissue clocks contribute to this effect. To reveal the impact of the circadian timing system on lipid metabolism, blood and adipose tissue samples from wild-type, ...
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Morphological changes associated with mobilization of lipid were studied in epididymal adipose tissue from fasted and from alloxan diabetic rats. In both groups of animals a decrease in lipid content was accompanied by the formation of complex frond-like cytoplasmic processes and of loops and folds of basement membrane which extended from cell surfaces. These changes, evident after 1 day of fas...
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In order to know the ultrastructural particularities of the adipose tissues, especially when very accurate in situ location of some molecules of interest (mRNA, proteins) must be identified in their associations with specific infrastructures during adipogenesis correlated with the fat type body location, the electron microscopic investigation is the best way to get it. We analysed the subcutane...
متن کاملCentral sympathetic innervations to visceral and subcutaneous white adipose tissue.
There is a link between visceral white adipose tissue (WAT) and the metabolic syndrome in humans, with health improvements produced with small visceral WAT reduction. By contrast, subcutaneous WAT provides a site for lipid storage that is rather innocuous relative to ectopic lipid storage in muscle or liver. The sympathetic nervous system (SNS) is the principal initiator for lipolysis in WAT by...
متن کاملLipid mobilization in subcutaneous adipose tissue during exercise in lean and obese humans. Roles of insulin and natriuretic peptides.
The aim of this study was to evaluate the relative contributions of various hormones involved in the regulation of lipid mobilization in subcutaneous adipose tissue (SCAT) during exercise and to assess the impact of obesity on this regulation. Eight lean and eight obese men performed a 60-min cycle exercise bout at 50% of their peak oxygen uptake on two occasions: during intravenous infusion of...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2020
ISSN: 0022-2275
DOI: 10.1194/jlr.ra120000869